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1987-10-07
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582b
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16 lines
IN PATIENTS WITH RENAL IMPAIRMENT, AMPICILLIN DOSAGE SHOULD
BE CAREFULLY ADJUSTED TO AVOID TOXICITY (ALLERGIC
INTERSTITIAL NEPHRITIS, SEIZURES, AND COAGULOPATHY).
SOME CLINICIANS RECOMMEND THAT THE DOSAGE REGIMEN BE
ADJUSTED BASED ON THE PATIENT'S CREATININE CLEARANCE:
CREATININE
CLEARANCE DOSAGE INTERVAL
(ML/MINUTE)
10-50 6 to 12 hours
<10 12 to 16 hours